Areas of uncertainties and unmet needs in bipolar disorders: clinical and research perspectives
The Lancet Psychiatry
Fecha de publicación: 23 august 2018
Autores: Prof Michael Bauer, MD., Prof Ole A Andreassen, MD.,Prof John R Geddes, MD., Prof Lars Vedel Kessing, MD., Ute Lewitzka, MD., Prof Thomas G Schulze, MD., Prof Eduard Vieta, MD
Background: This Review discusses crucial areas related to the identification, clinical presentation, course, and therapeutic management of bipolar disorder, a major psychiatric illness. Bipolar disorder is often misdiagnosed, leading to inappropriate, inadequate, or delayed treatment. Even when bipolar disorder is successfully diagnosed, its clinical management presents several major challenges, including how best to optimise treatment for an individual patient, and how to balance the benefits and risks of polypharmacy.