Cognitive decline profiles differ in Parkinson disease dementia and dementia with Lewy bodies
Neurology Journal
Fecha de publicación: 24 April 2020
DOI: https://doi.org/10.1212/WNL.0000000000009434
Autores: Denis S. Smirnov, Douglas Galasko, Steven D. Edland, J. Vincent Filoteo, Lawrence A. Hansen, David P. Salmon
Background: To examine whether domain-specific patterns of cognitive impairment and trajectories of decline differed in patients with clinically diagnosed Parkinson disease dementia (PDD) (N = 29) and autopsy-confirmed dementia with Lewy bodies (DLB) (N = 58) or Alzheimer disease (AD) (N = 174) and to determine the impact of pooling patients with PDD and DLB in clinical trials targeting cognition.
