Fecha de publicación: 23 December 2020
Autores: Kimford J. Meador, Page B. Pennell, Ryan C. May, Carrie A. Brown, Gus Baker, Rebecca Bromley, David W. Loring, Morris J. Cohen, for the NEAD Investigator Group
Background: Emerging evidence suggests potential positive neuropsychological effects of periconceptional folate in both healthy children and children exposed in utero to antiseizure medications (ASMs). In this report, we test the hypothesis that periconceptional folate improves neurodevelopment in children of women with epilepsy by re-examining data from the Neurodevelopmental Effects of Antiepileptic Drugs (NEAD) study.