Absence of cerebrospinal fluid antineuronal antibodies in schizophrenia spectrum disorders
British Journal Psychiatry
Fecha de publicación: 28 March 2018
DOI: https://doi.org/10.1192/bjp.2018.24
Autores: Tatiana Oviedo-Salcedo, Lot de Witte, Tania Kümpfel, René S. Kahn
Background: Antibody-mediated encephalitis has been discussed as one possible cause for isolated psychotic syndromes. Mostly based on serum samples, findings have been controversial. We present the results of a retrospective study of 124 clinically diagnosed psychotic patients without documented relevant neurological symptoms. All were tested for different antineuronal antibodies in cerebrospinal fluid (CSF) while 81 received serum testing.
