Antipsychotics and Their Impact on Cerebral White Matter: Part of the Problem or Part of the Solution?

American Journal of Psychiatry

Fecha de publicación: 1 november

DOI: https://doi.org/10.1176/appi.ajp.2018.18060752

Autores: Marek Kubicki , M.D., Ph.D., Amanda E. Lyall , Ph.D

Background: The dysmyelination hypothesis of schizophrenia proposes that dysfunctional oligodendrocytes, the class of glial cells responsible for producing and maintaining myelin within the central nervous system, may lead to a disruption in short- and long-distance communication between neural cells.

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