Associations of Fully Automated CSF and Novel Plasma Biomarkers With Alzheimer Disease Neuropathology at Autopsy
Neurology Journal
Fecha de publicación: 15 de julio de 2021
Autores: Michel J. Grothe, Alexis Moscoso, Nicholas J. Ashton, Thomas K. Karikari, Juan Lantero-Rodriguez, Anniina Snellman, Henrik Zetterberg, Kaj Blennow, Michael Schöll, for the Alzheimer’s Disease Neuroimaging Initiative
DOI: https://doi.org/10.1212/WNL.0000000000012513
Background: To study CSF biomarkers of Alzheimer disease (AD) analyzed by fully automated Elecsys immunoassays compared to neuropathologic gold standards and to compare their accuracy to plasma phosphorylated tau (p-tau181) measured with a novel single molecule array method.