Gerontology
Fecha de publicación: October 2017
DOI: https://doi.org/10.1159/000478012
Autores: Watad A., Bragazzi N.L., Adawi M., Amital H., Toubi E., Porat B.-S., Shoenfeld Y.
Background: Advancements in the field of biomedicine, including the control of infectious diseases through antibiotics and vaccination practices and the prevention of chronic disorders, have led to reduced mortality, increased life expectancy and, as such, growth of the older population. Ageing is accompanied by profound morphological and physiological alterations. In particular, the immune system undergoes a complex series of remodeling/restructuring events, involving almost all compartments – both the innate and the adaptive system.