Autoimmunity in the Elderly: Insights from Basic Science and Clinics

Gerontology

Fecha de publicación: October 2017

DOI: https://doi.org/10.1159/000478012

Autores: Watad A., Bragazzi N.L., Adawi M., Amital H., Toubi E., Porat B.-S., Shoenfeld Y.

Background: Advancements in the field of biomedicine, including the control of infectious diseases through antibiotics and vaccination practices and the prevention of chronic disorders, have led to reduced mortality, increased life expectancy and, as such, growth of the older population. Ageing is accompanied by profound morphological and physiological alterations. In particular, the immune system undergoes a complex series of remodeling/restructuring events, involving almost all compartments – both the innate and the adaptive system.

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