Blood pressure control and clinical outcomes in acute intracerebral haemorrhage: a preplanned pooled analysis of individual participant data
The Lancet Neurology
Fecha de publicación: September 2019
DOI: https://doi.org/10.1016/S1474-4422(19)30196-6
Autores: Tom J Moullaali, MBBS., Xia Wang, PhD., Reneé H Martin, PhD.,
Virginia B Shipes, BSc., Prof Thompson G Robinson, MD., Prof John Chalmers, PhD., et al.
Background: Uncertainty persists over the effects of blood pressure lowering in acute intracerebral haemorrhage. We aimed to combine individual patient-level data from the two largest randomised controlled trials of blood pressure lowering strategies in patients with acute intracerebral haemorrhage to determine the strength of associations between key measures of systolic blood pressure control and safety and efficacy outcomes.