Challenges in the diagnosis of Parkinson’s disease

The Lancet Neurology

Fecha de publicación: Mayo de 2021

Autores: Prof Eduardo Tolosa, PhD  , Alicia Garrido, MD, Sonja W Scholz, MD, Prof Werner Poewe, PhD 


Background: Parkinson’s disease is the second most common neurodegenerative disease and its prevalence has been projected to double over the next 30 years. An accurate diagnosis of Parkinson’s disease remains challenging and the characterisation of the earliest stages of the disease is ongoing. Recent developments over the past 5 years include the validation of clinical diagnostic criteria, the introduction and testing of research criteria for prodromal Parkinson’s disease, and the identification of genetic subtypes and a growing number of genetic variants associated with risk of Parkinson’s disease.

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