Circadian rhythm and epilepsy

The Lancet Neurology

Fecha de publicación: 23 october 2018


Autores: Sofia Khan, MD., Lino Nobili, MD., Ramin Khatami, MD., Tobias Loddenkemper, MD., Christian Cajochen, PhD., Derk-Jan Dijk, PhD

Background: Advances in diagnostic technology, including chronic intracranial EEG recordings, have confirmed the clinical observation of different temporal patterns of epileptic activity and seizure occurrence over a 24-h period. The rhythmic patterns in epileptic activity and seizure occurrence are probably related to vigilance states and circadian variation in excitatory and inhibitory balance.

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