The Lancet Neurology
Fecha de publicación: 23 october 2018
DOI: https://doi.org/10.1016/S1474-4422(18)30335-1
Autores: Sofia Khan, MD., Lino Nobili, MD., Ramin Khatami, MD., Tobias Loddenkemper, MD., Christian Cajochen, PhD., Derk-Jan Dijk, PhD
Background: Advances in diagnostic technology, including chronic intracranial EEG recordings, have confirmed the clinical observation of different temporal patterns of epileptic activity and seizure occurrence over a 24-h period. The rhythmic patterns in epileptic activity and seizure occurrence are probably related to vigilance states and circadian variation in excitatory and inhibitory balance.
