Cognition and behaviour in frontotemporal dementia with and without amyotrophic lateral sclerosis

Journal of Neurology, Neurosurgery & Psychiatry

Fecha de publicación: October 14, 2020


Autores: Jennifer A Saxon,  Jennifer C Thompson,  Jennifer M Harris, Anna M Richardson, Tobias Langheinrich, Sara Rollinson, Stuart Pickering-Brown, Amina Chaouch, John Ealing, Hisham Hamdalla, Carolyn A Young, Dan Blackburn, Tahir Majeed, Claire Gall, Matthew Jones, Julie S Snowden.

Background: The precise relationship between frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) is incompletely understood. The association has been described as a continuum, yet data suggest that this may be an oversimplification. Direct comparisons between patients who have behavioural variant FTD (bvFTD) with and without ALS are rare. This prospective comparative study aimed to determine whether there are phenotypic differences in cognition and behaviour between patients with FTD-ALS and bvFTD alone.

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