Cognitive Change in Schizophrenia and Other Psychoses in the Decade Following the First Episode

American Journal of Psychiatry

Fecha de publicación:


Autores: Jolanta Zanelli , Ph.D., Josephine Mollon , Ph.D., Sven Sandin , Ph.D., Craig Morgan , Ph.D., Paola Dazzan , M.D., Ph.D., Izabela Pilecka , Ph.D., Tiago Reis Marques , M.D., Ph.D., Anthony S. David , M.D., et al.

Background: Schizophrenia is associated with a marked cognitive impairment that is widely believed to remain stable after illness onset. Yet, to date, 10-year prospective studies of cognitive functioning following the first episode with good methodology are rare. The authors examined whether schizophrenia patients experience cognitive decline after the first episode, whether this decline is generalized or confined to individual neuropsychological functions, and whether decline is specific to schizophrenia.

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