Cognitive decline profiles differ in Parkinson disease dementia and dementia with Lewy bodies

Neurology Journal

Fecha de publicación: 24 April 2020


Autores: Denis S. Smirnov, Douglas Galasko, Steven D. Edland, J. Vincent Filoteo, Lawrence A. Hansen, David P. Salmon

Background: To examine whether domain-specific patterns of cognitive impairment and trajectories of decline differed in patients with clinically diagnosed Parkinson disease dementia (PDD) (N = 29) and autopsy-confirmed dementia with Lewy bodies (DLB) (N = 58) or Alzheimer disease (AD) (N = 174) and to determine the impact of pooling patients with PDD and DLB in clinical trials targeting cognition.

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