Cognitive function following a major depressive episode: a systematic review and meta-analysis

The Lancet Psychiatry

Fecha de publicación: 15 August 2019

DOI: https://doi.org/10.1016/S2215-0366(19)30291-3

Autores: Maria Semkovska, Lisa Quinlivan, Tara O’Grady, Rebecca Johnson, Aisling Collins, Jessica O’Connor, Hannah Knittle, Elayne Ahern, Taylor Gload.

Background: Substantial evidence suggests that cognitive deficits might persist after remission of a major depressive episode. However, results are inconsistent relative to the importance, pattern, severity, and moderating factors of this impairment. We aimed to determine how cognitive function following a major depressive episode compares with normal function, to specify the pattern and severity of persistent cognitive dysfunctions, and to examine the potential moderator effect of ten prespecified clinical and demographic variables.

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