Defining causality in COVID-19 and neurological disorders

Journal of Neurology, Neurosurgery & Psychiatry

Fecha de publicación: 5 June 2020


Autores: Mark Ellul, Aravinthan Varatharaj, Timothy R Nicholson, Thomas Arthur Pollak, Naomi Thomas, Ava Easton, Michael S Zandi, Hadi Manji, Tom Solomon, et al.

Background: Clinicians are increasingly recognising neurological presentations occur in some patients. A case series from Wuhan described associated neurological syndromes (eg, ‘dizziness’ and ‘impaired consciousness’), but with little detail regarding symptomatology, and cerebrospinal fluid (CSF) and neuroimaging findings. The extent to which these disorders were caused by the virus per se, rather than being complications of critical illness, unmasking of degenerative disease, or iatrogenic effects of repurposed medications is not clear.

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