Developmental Contributions of Schizophrenia Risk Alleles and Childhood Peer Victimization to Early-Onset Mental Health Trajectories
American Journal of Psychiatry
Fecha de publicación: 29 november 2018
DOI: https://doi.org/10.1176/appi.ajp.2018.18010075
Autores: Lucy Riglin , Ph.D., Gemma Hammerton , Ph.D., Jon Heron , Ph.D., Stephan Collishaw , Ph.D., Louise Arseneault , Ph.D., Ajay K. Thapar , M.R.C.G.P., Ph.D., Barbara Maughan , Ph.D., Michael C. O’Donovan , F.R.C.Psych., Ph.D., Anita Thapar , F.R.C.Psych., Ph.D.
Background: Twin studies suggest that genetic factors contribute to continuity in mental health problems and that environmental factors are the major contributor to developmental change. The authors investigated the influence of psychiatric risk alleles on early-onset mental health trajectories and whether the trajectories were subsequently modified by exposure to childhood victimization.