Diagnosis- and Cell Type-Specific Mitochondrial Functional Pathway Signatures in Schizophrenia and Bipolar Disorder

American Journal of Psychiatry

Fecha de publicación: 29 Oct 2020

DOI: https://doi.org/10.1176/appi.ajp.2020.19111210

Autores: Jill R. Glausier, Ph.D., John F. Enwright III, Ph.D., David A. Lewis, M.D.

Background: The shared risk factors and clinical features in schizophrenia and bipolar disorder may be linked via mitochondrial dysfunction. However, the severity of mitochondrial dysfunction, and/or the specific mitochondrial functional pathways affected, may differ between diagnoses, especially at the level of individual cell types.

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