Effectiveness of Rotigotine plus intensive and goal-based rehabilitation versus Rotigotine alone in “de-novo” Parkinsonian subjects
Journal of Neurology
Fecha de publicación: 13 February 2018
DOI: https://doi.org/10.1007/s00415-018-8792-0
Autores: D. Ferrazzoli, P. Ortelli, G. Riboldazzi, R. Maestri, G. Frazzitta
Background: Dopamine Replacement Therapy (DRT) represents the most effective treatment for Parkinson’s disease (PD). Nevertheless, several symptoms are unresponsive to treatment and its long-term use leads to serious side effects. To optimize the pharmacological management of PD, dopamine-agonists are often prescribed to “de-novo” patients. Moreover, several studies have shown the effectiveness and the synergic effect of rehabilitation in treating PD.
