Effects of intensive versus standard blood pressure control on domain-specific cognitive function: a substudy of the SPRINT randomised controlled trial

The Lancet Neurology

Fecha de publicación: November 01, 2020

DOI: https://doi.org/10.1016/S1474-4422(20)30319-7

Autores: Prof Stephen R Rapp, PhD , Sarah A Gaussoin, MS, Prof Bonnie C Sachs, PhD, Prof Gordon Chelune, PhD, Prof Mark A Supiano, MD, Prof Alan J Lerner, MD

Background: Results from the Systolic Blood Pressure Intervention Trial (SPRINT) showed that intensive control of systolic blood pressure significantly reduced the occurrence of mild cognitive impairment, but not probable dementia. We investigated the effects of intensive lowering of systolic blood pressure on specific cognitive functions in a preplanned substudy of participants from SPRINT.

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