Functional connectivity of large-scale brain networks in patients with anti-NMDA receptor encephalitis: an observational study
The Lancet Psychiatry
Fecha de publicación: 04 September 2017
Autores: Michael Peer, MSc, Harald Prüss, MD, Inbal Ben-Dayan, BSc, Dr Friedemann Paul, MD’Correspondence information about the author Dr Friedemann PaulEmail the author Dr Friedemann Paul, Shahar Arzy, MD†, Carsten Finke, MD†
Background: In anti-NMDA receptor (NMDAR) encephalitis, antibody-mediated dysfunction of NMDARs causes severe neuropsychiatric symptoms, including psychosis, memory deficits, and movement disorders. However, it remains elusive how antibody-mediated NMDAR dysfunction leads to these symptoms, and whether the symptoms arise from impairment in specific brain regions and the interactions between impaired regions.