Longitudinal thalamic white and grey matter changes associated with visual hallucinations in Parkinson’s disease

Journal of Neurology, Neurosurgery & Psychiatry

Fecha de publicación: Enero de 2022

Autores: Angeliki Zarkali, Peter McColgan, Louise Ann Leyland, Andrew John Lees, Rimona Sharon Weil

DOI: Journal of Neurology, Neurosurgery & Psychiatry 2022;93:169-179

Objective: Visual hallucinations are common in Parkinson’s disease (PD) and associated with worse outcomes. Large-scale network imbalance is seen in PD-associated hallucinations, but mechanisms remain unclear. As the thalamus is critical in controlling cortical networks, structural thalamic changes could underlie network dysfunction in PD hallucinations.