Maternal prenatal depressive symptoms and risk for early-life psychopathology in offspring: genetic analyses in the Norwegian Mother and Child Birth Cohort Study

The Lancet Psychiatry

Fecha de publicación: 20 september 2018


Autores: Laurie J Hannigan, PhD., Espen Moen Eilertsen, PhD., Line C Gjerde, PhD., Ted Reichborn-Kjennerud, MD., Prof Thalia C Eley, PhD., Fruhling V Rijsdijk, PhD., Eivind Ystrom, PhD., Tom A McAdams, PhD 

Background: Maternal prenatal depression is a known risk factor for early-life psychopathology among offspring; however, potential risk transmission mechanisms need to be distinguished. We aimed to test the relative importance of passive genetic transmission, direct exposure, and indirect exposure in the association between maternal prenatal depressive symptoms and early-life internalising and externalising psychopathology in offspring.

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