Midlife cardiovascular fitness and dementia A 44-year longitudinal population study in women

Neurology Journal

Fecha de publicación: March 14, 2018

DOI: 10.1212/WNL.0000000000005290

Autores: Helena Hörder, Lena Johansson, XinXin Guo, Gunnar Grimby, Silke Kern, Svante Östling and Ingmar Skoog

Background: A population-based sample of 1,462 women 38 to 60 years of age was examined in 1968. Of these, a systematic subsample comprising 191 women completed a stepwise-increased maximal ergometer cycling test to evaluate cardiovascular fitness. Subsequent examinations of dementia incidence were done in 1974, 1980, 1992, 2000, 2005, and 2009.