Muscle and not neuronal biomarkers correlate with severity in spinal and bulbar muscular atrophy
Neurology Journal
Fecha de publicación: 20 February 2019
DOI: https://doi.org/10.1212/WNL.0000000000007097
Autores: Vittoria Lombardi, Giorgia Querin, Oliver J. Ziff, Luca Zampedri, Ilaria Martinelli, Carolin Heller, Martha Foiani, Cinzia Bertolin, Ching-Hua Lu, et al.
Background: To determine whether blood biomarkers of neuronal damage (neurofilament light chain [NfL]), muscle damage (creatine kinase [CK]), and muscle mass (creatinine) are altered in spinal and bulbar muscular atrophy (SBMA) and can be used as biomarkers for disease severity.
