Muscle and not neuronal biomarkers correlate with severity in spinal and bulbar muscular atrophy

Neurology Journal

Fecha de publicación: 20 February 2019


Autores: Vittoria Lombardi, Giorgia Querin, Oliver J. Ziff, Luca Zampedri, Ilaria Martinelli, Carolin Heller, Martha Foiani, Cinzia Bertolin, Ching-Hua Lu, et al.

Background: To determine whether blood biomarkers of neuronal damage (neurofilament light chain [NfL]), muscle damage (creatine kinase [CK]), and muscle mass (creatinine) are altered in spinal and bulbar muscular atrophy (SBMA) and can be used as biomarkers for disease severity.

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