Neural effects of oxytocin and mimicry in frontotemporal dementia

Neurology Journal

Fecha de publicación: 22 September 2020

DOI: https://doi.org/10.1212/WNL.0000000000010933

Autores: Lindsay D. Oliver, Chloe Stewart, Kristy Coleman, James H. Kryklywy, Robert Bartha, Derek G.V. Mitchell, Elizabeth C. Finger

Background: The objective of this study was to determine whether intranasal oxytocin, alone or in combination with instructed mimicry of facial expressions, would augment neural activity in patients with FTD in brain regions associated with empathy, emotion processing and the simulation network, as indexed by blood-oxygen-level dependent (BOLD) signal during functional magnetic resonance imaging (fMRI).

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