Progressive Neurochemical Abnormalities in Cognitive and Motor Subgroups of Amyotrophic Lateral Sclerosis
Neurology
Fecha de publicación: 14 de junio de 2021
Autores: Daniel Ta, Abdullah Ishaque, Ojas Srivastava, Chris Hanstock, Peter Seres, Dean T. Eurich, Collin Luk, Hannah Briemberg, Richard Frayne, Angela L. Genge, Simon J. Graham, Lawrence Korngut, Lorne Zinman, Sanjay Kalra
DOI: https://doi.org/10.1212/WNL.0000000000012367
Objective: To evaluate progressive cerebral degeneration in amyotrophic lateral sclerosis (ALS) by assessing alterations in N-acetylaspartate (NAA) ratios in the motor and prefrontal cortex within clinical subgroups of ALS.