Psychological and psychosocial interventions for negative symptoms in psychosis: systematic review and meta-analysis

The British Journal of Psychiatry
May 2017, 210 (5) 324-332

Danyael Lutgens, Genevieve Gariepy, Ashok Malla


Background: Negative symptoms observed in patients with psychotic disorders undermine quality of life and functioning. Antipsychotic medications have a limited impact. Psychological and psychosocial interventions, with medication, are recommended. However, evidence for the effectiveness of specific non-biological interventions warrants detailed examination.

Aims: To conduct a meta-analytic and systematic review of the literature on the effectiveness of non-biological treatments for negative symptoms in psychotic disorders.

Method: We searched for randomised controlled studies of psychological and psychosocial interventions in psychotic disorders that reported outcome on negative symptoms…

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