Safety and efficacy of prednisone versus placebo in short-term prevention of episodic cluster headache: a multicentre, double-blind, randomised controlled trial


The Lancet Neurology

Fecha de publicación: November 24, 2020

DOI: https://doi.org/10.1016/S1474-4422(20)30363-X

Autores: Prof Mark Obermann, Steffen Nägel, Prof Claudia Ose, Nilüfer Sonuc, Prof André Scherag, Peter Storch, et al.

Background: Prednisone is commonly used for initial short-term therapy of episodic cluster headaches before preventive medication such as verapamil becomes effective, but this strategy has not been tested in large randomised trials. We aimed to access the safety and efficacy of this treatment approach.

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