Serum neurofilament light chain as outcome marker for intensive care unit patients

Neurology Journal

Fecha de publicación: 23 de octubre de 2021


Autores: Anna Lena Fisse, Kalliopi Pitarokoili, David Leppert, Jeremias Motte, Xiomara Pedreiturria, Ludwig Kappos, Ralf Gold, Jens Kuhle & Min-Suk Yoon 

Background: Neurofilament light chain (NfL) in serum indicates neuro-axonal damage in diseases of the central and peripheral nervous system. Reliable markers to enable early estimation of clinical outcome of intensive care unit (ICU) patients are lacking. The aim of this study was to investigate, whether serum NfL levels are a possible biomarker for prediction of outcome of ICU patients.

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