Sleep Onset Problems and Subcortical Development in Infants Later Diagnosed With Autism Spectrum Disorder

American Journal of Psychiatry

Fecha de publicación: 7 May 2020


Autores: Katherine E. MacDuffie, Ph.D., Mark D. Shen, Ph.D., Stephen R. Dager, M.D., Martin A. Styner, Ph.D., Sun Hyung Kim, Ph.D., Sarah Paterson, Ph.D., Juhi Pandey, Ph.D., Tanya St. John, Ph.D., Jed T. Elison, Ph.D., Jason J. Wolff, Ph.D., et al.

Background: Sleep patterns in children with autism spectrum disorder (ASD) appear to diverge from typical development in the second or third year of life. Little is known, however, about the occurrence of sleep problems in infants who later develop ASD and possible effects on early brain development. In a longitudinal neuroimaging study of infants at familial high or low risk for ASD, parent-reported sleep onset problems were examined in relation to subcortical brain volumes in the first 2 years of life.

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