Smoking, symptoms, and quality of life in patients with psychosis, siblings, and healthy controls: a prospective, longitudinal cohort study

Lancet Psychiatry

Fecha de publicación: 5 december 2018



Jentien Vermeulen, MD., Frederike Schirmbeck, PhD., Matthijs Blankers, PhD., Mirjam van Tricht, PhD., Prof Wim van den Brink, PhD., Prof Lieuwe de Haan, PhD., et al.

Background: The self-medication hypothesis postulates that the high prevalence of smoking in patients with psychosis can be explained by the ameliorating effect of smoking on symptoms. However, there are few large prospective studies testing this hypothesis. We aimed to examine the multi-cross-sectional and prospective associations of changes in smoking behaviour with symptoms and quality of life.

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