Subthalamic suppression defines therapeutic threshold of deep brain stimulation in Parkinson’s disease
Journal of Neurology, Neurosurgery & Psychiatry
Fecha de publicación: 12 September 2019
DOI: http://dx.doi.org/10.1136/jnnp-2019-321140
Autores: Luka Milosevic, Suneil K Kalia, Mojgan Hodaie, Andres Lozano, Milos R Popovic, William Hutchison
Background: Subthalamic deep brain stimulation (DBS) is beneficial when delivered at a high frequency. However, the effects of current amplitude and pulse width on subthalamic neuronal activity during high-frequency stimulation have not been investigated.