Telomere Attrition: A Window Into Common Mental Disorders and Cellular Aging

The American Journal of Psychiatry
Volume 173, Issue 6, June 01, 2016, pp. 556-558

Charles F. Reynolds III


In this issue of the Journal, Verhoeven and colleagues (1) further document the association between depressive and anxiety disorders and shorter leukocyte telomere lenght (LTL), an indicator of cellurar aging. The researchers, reporting data from 2,936 participants in the Netherlands Study of Depression and Anxienty (NESDA) (2), observed that particpants with remitted and with current depressive and anxiety disorders show shorter LTL that never affected controls across baseline and 6-year follow-up.

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