The role of astroglia in Alzheimer’s disease: pathophysiology and clinical implications

The Lancet Neurology

Fecha de publicación: February 2019


Autores: Amaia M. Arranz, PhD., Bart De Strooper, Md

Background: Astrocytes, also called astroglia, maintain homoeostasis of the brain by providing trophic and metabolic support to neurons. They recycle neurotransmitters, stimulate synaptogenesis and synaptic neurotransmission, form part of the blood–brain barrier, and regulate regional blood flow. Although astrocytes have been known to display morphological alterations in Alzheimer’s disease for more than a century, research has remained neurocentric.

Seguir leyendo

Enviar comentario