The Lancet Neurology
Fecha de publicación: 23 November 2017
DOI: http://dx.doi.org/10.1016/S1474-4422(17)30405-2
Autores: Jan Hoffmann, Arne May.
Objective: Cluster headache is a trigeminal autonomic cephalalgia characterised by extremely painful, strictly unilateral, short-lasting headache attacks accompanied by ipsilateral autonomic symptoms or the sense of restlessness and agitation, or both. The severity of the disorder has major effects on the patient’s quality of life and, in some cases, might lead to suicidal ideation. Cluster headache is now thought to involve a synchronised abnormal activity in the hypothalamus, the trigeminovascular system, and the autonomic nervous system.
