Human cerebral evolution and the clinical syndrome of amyotrophic lateral sclerosis

Journal of Neurology, Neurosurgery & Psychiatry

Fecha de publicación: 11 April 2019

DOI: http://dx.doi.org/10.1136/jnnp-2017-317245

Autores: Robert D Henderson, Fleur C Garton, Matthew C Kiernan, Martin R Turner, Andrew Eisen.

Background: The adult neurodegenerative disorder amyotrophic lateral sclerosis (ALS) is unmistakeable from clinical descriptions now more than a century old. Neither the site of symptom onset in ALS nor pattern of symptom spread is truly random.

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