Neurology Journal
Fecha de publicación: 23 de octubre de 2021
DOI: https://doi.org/10.1007/s00415-020-10277-9
Autores: Anna Lena Fisse, Kalliopi Pitarokoili, David Leppert, Jeremias Motte, Xiomara Pedreiturria, Ludwig Kappos, Ralf Gold, Jens Kuhle & Min-Suk Yoon
Background: Neurofilament light chain (NfL) in serum indicates neuro-axonal damage in diseases of the central and peripheral nervous system. Reliable markers to enable early estimation of clinical outcome of intensive care unit (ICU) patients are lacking. The aim of this study was to investigate, whether serum NfL levels are a possible biomarker for prediction of outcome of ICU patients.