The Relationship Between White Matter Microstructure and General Cognitive Ability in Patients With Schizophrenia and Healthy Participants in the ENIGMA Consortium
American Journal of Psychiatry
Fecha de publicación: 26 March 2020
DOI: https://doi.org/10.1176/appi.ajp.2019.19030225
Autores: Laurena Holleran, Ph.D., Sinead Kelly, Ph.D., Clara Alloza, Ph.D., Ingrid Agartz, M.D., Ph.D., Ole A. Andreassen, M.D., Ph.D., Celso Arango, M.D., Ph.D., Nerisa Banaj, Ph.D., Vince Calhoun, Ph.D., Dara Cannon, Ph.D., Vaughan Carr, M.D., Aiden Corvin, M.R.C.Psych., Ph.D., David C. Glahn, et al.
Background: Schizophrenia has recently been associated with widespread white matter microstructural abnormalities, but the functional effects of these abnormalities remain unclear. Widespread heterogeneity of results from studies published to date preclude any definitive characterization of the relationship between white matter and cognitive performance in schizophrenia.